Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy in paediatric patients with multiple sclerosis: Results from the PARADIGMS study.

Tanuja ChitinisBrenda BanwellLauren B KruppDouglas L ArnoldAmit Bar-OrWolfgang BrückGavin GiovannoniBenjamin GreenbergAngelo GhezziEmmanuelle WaubantKevin RostasyKumaran DeivaPeter HuppkeJerry S WolinskyYing ZhangAmin AzmonAnnik K-LaflammeRajesh KaranJutta Gärtner

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

In paediatric patients, the overall incidence of infections was comparable between fingolimod and interferon. No association was observed between nadir ALC and infections in POMS, although sample size may have been too small to rule an association.

Keyphrases

multiple sclerosis
end stage renal disease
intensive care unit
emergency department
newly diagnosed
chronic kidney disease
peripheral blood
prognostic factors
risk factors
peritoneal dialysis
dendritic cells
mesenchymal stem cells
immune response
cell therapy
smoking cessation