Multicentre study and systematic review: Allopurinol exposure during pregnancy.
Femke CrouwelMelek SimsekMarjon A de BoerDirk P van AsseldonkAbha BhallaAngelique L M WeusthuisLennard P L GilissenRobert J VerburgWout G N MaresBindia JharapJohan P KuijvenhovenBas OldenburgHans J C BuiterMette JulsgaardNanne K de BoerPublished in: Alimentary pharmacology & therapeutics (2024)
Overall, the teratogenicity of allopurinol remains inconclusive. Children conceived by mothers treated for IBD with allopurinol/thiopurine co-therapy do not seem to have an increased risk of congenital anomalies.