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Photoenzymes for Radical C-C Coupling.

Rui GuoHeyu ChenYang Yang
Published in: Nature catalysis (2022)
General catalytic methods for free radical-mediated asymmetric transformations have long eluded synthetic organic chemists. Now, NAD(P)H-dependent ketoreductases (KREDs) are repurposed and engineered as highly efficient photoenzymes to catalyse asymmetric radical C-C couplings.
Keyphrases
  • highly efficient
  • solid state