Evolution of the recombination regulator PRDM9 in minke whales.

Elena Damm Kristian Karsten UllrichWilliam B AmosLinda Odenthal-Hesse

Published in: BMC genomics (2022)

The PRDM9 ZnF array evolves rapidly, in minke whales, with at least one DNA-recognizing position under positive selection. Extensive PRDM9 diversity is observed, particularly in the Antarctic in minke whales. Common minke whales shared a specific Prdm9 allele across subspecies boundaries, suggesting incomplete speciation by the mechanisms associated with PRDM9 hybrid sterility.

Keyphrases

dna damage
transcription factor
high resolution
high throughput
cell free
dna repair
circulating tumor
mass spectrometry
high density
organic matter