BCL6 attenuates hyperoxia-induced lung injury by inhibiting NLRP3-mediated inflammation in fetal mouse.

Dan ChenHui-Min ZhaoXian-Hui DengSheng-Peng LiMei-Hui ZhouYa-Xian WuYing TongRen-Qiang YuQing-Feng Pang

Published in: Experimental lung research (2024)

BCL6 inhibits NLRP3-mediated inflammation, attenuates alveolar simplification and dysregulated pulmonary vessel development in hyperoxia-induced BPD mice. Hence, BCL6 may be a target in treating BPD and neonatal diseases.

Keyphrases

oxidative stress
diabetic rats
high glucose
drug induced
pulmonary hypertension
signaling pathway
type diabetes
adipose tissue
endothelial cells
metabolic syndrome
high fat diet induced
skeletal muscle
insulin resistance