Colorectal cancer detected by liquid biopsy 2 years prior to clinical diagnosis in the HUNT study.

Siv S BrennePoul Henning MadsenInge Sokilde PedersenKristian HveemFrank SkorpenHenrik Bygum Krarup Guro Fanneløb GiskeødegårdEivor A Laugsand

Published in: British journal of cancer (2023)

Detection of known methylated ctDNA markers of CRC is possible up to 2 years prior to the clinical diagnosis in an unselected population resembling the screening setting. This study supports the hypothesis that some patients could be diagnosed earlier, if ctDNA detection was part of the CRC screening programme.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
clinical trial
patient reported outcomes
patient reported