Detection of Resistance to Fluoroquinolones and Second-Line Injectable Drugs Among Mycobacterium tuberculosis by a Reverse Dot Blot Hybridization Assay.
Guilian LiQian GuoHai-Can LiuLi WanYi JiangMachao LiLi-Li ZhaoXiuqin ZhaoZhiguang LiuKanglin WanPublished in: Infection and drug resistance (2020)
Our data suggested that compared to sequencing, the RDBH assay could serve as a rapid and reliable method for testing the resistance of M. tuberculosis against OFX and SLIDs, enabling early administration of appropriate treatment regimens among MDR tuberculosis patients.
Keyphrases
- mycobacterium tuberculosis
- end stage renal disease
- pulmonary tuberculosis
- high throughput
- ejection fraction
- loop mediated isothermal amplification
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- single cell
- big data
- machine learning
- single molecule
- patient reported outcomes
- artificial intelligence
- real time pcr
- drug induced
- replacement therapy