Low-dose-rate ionizing radiation affects innate immunity protein IFITM3 in a mouse model of Alzheimer's disease.

Yeonghoon SonChang Geun LeeJoong Sun KimHae-June Lee

Published in: International journal of radiation biology (2023)

Therefore, this study revealed the possibility that LDR could affect the progression of AD, which may be associated with decreased IFN-related signaling, especially IFITM3. Our findings suggest that further studies are required regarding the potential role of LDR in the progression of AD.

Keyphrases

low dose
mouse model
dendritic cells
immune response
high dose
cognitive decline
protein protein
small molecule
case control
risk assessment