Establishment and Characterization of Multi-Drug Resistant p53-Negative Osteosarcoma SaOS-2 Subline.

Sergei V Boichuk Firyuza BikinievaElena ValeevaPavel DunaevMaria VasilevaPavel B KopninEkaterina MikheevaTatyana IvoilovaIlshat MustafinGalembikova Aigul

Published in: Diagnostics (Basel, Switzerland) (2023)

An acquired resistance of OS to the chemotherapeutic agents might be due to the several mechanisms undergoing simultaneously on the single-cell level. This reveals the complexity of the mechanisms involved in the secondary resistance of OS to chemotherapies.

Keyphrases

drug resistant
multidrug resistant
single cell
acinetobacter baumannii
rna seq
high throughput