A Thermally Induced Hydride Transfer from an Amine to an Allene Triggers an Annulation Reaction, Giving Dihydrofuropyridinones.

Wei SunDharyl C WilsonMark E LightDavid C Harrowven

Published in: Organic letters (2018)

A thermal rearrangement leading to dihydrofuropyridinones and related polycyclic ring systems from furanones and cyclobutenones is described. A key feature of the reaction is the thermally induced hydride transfer from a 3°-amine to a conjugated allene to trigger cyclization.

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