Why does FFR-guided PCI improve clinical outcomes? The missing link of post-PCI ischemia reduction.
Arnold H SetoMorton J KernPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2019)
This study demonstrates that FFR-guided PCI reduces noninvasively assessed ischemia more effectively than angiography-guided PCI. Improved ischemia resolution was associated with improved clinical outcomes. Superior ischemia resolution is likely the dominant mechanism of improved outcomes with FFR in clinical outcome trials, as opposed to avoidance of inappropriate stenting and its associated adverse events.
Keyphrases
- antiplatelet therapy
- percutaneous coronary intervention
- coronary artery disease
- acute myocardial infarction
- acute coronary syndrome
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- atrial fibrillation
- coronary artery bypass grafting
- optical coherence tomography
- computed tomography
- single molecule
- heart failure
- skeletal muscle