An ELISA assay using a combination of recombinant proteins from multiple strains of Orientia tsutsugamushi offers an accurate diagnosis for scrub typhus.

Chien-Chung ChaoZhiwen ZhangTatyana BelinskayaWilawan ThipmontreeWiwit TantibhedyangkulSaowaluk SilpasakornEkkarat WongsawatYupin SuputtamongkolWei-Mei Ching

Published in: BMC infectious diseases (2017)

We have successfully developed an ELISA assay for the detection of Orientia-specific antibodies in serum that could provide effective screening of acute sera under clinical setup and it is also a useful assay to estimate seroprevalence in various endemic areas.

Keyphrases

high throughput
liver failure
respiratory failure
intensive care unit
monoclonal antibody
cell free
hepatitis b virus
extracorporeal membrane oxygenation