Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma.

John Wen-Cheng ChangChien-Jung HuangWen-Kuan HuangYu-Chao WangJia-Juan HsiehYao-Yu ChangYen-Lin HuangChia-Ling WuYeh-Han WangShu-Jen ChenKien Thiam TanChiao-Ping Chen Chiao-En Wu

Published in: Clinical & translational immunology (2023)

Genetic alterations in the p53 pathway may be critical in Asian patients with melanoma undergoing ICI treatment. Further investigation is required to explore this mechanism and validate these findings.

Keyphrases

copy number
skin cancer
gene expression
basal cell carcinoma
combination therapy