Magnetic resonance T1w/T2w ratio in the middle cerebellar peduncle might be a sensitive biomarker for multiple system atrophy.
Atsuhiko SugiyamaHajime YokotaShigeki HiranoGraham CooperHiroki MukaiKyosuke KoideJiaqi WangShoichi ItoCarsten FinkeAlexander U BrandtFriedemann PaulSatoshi KuwabaraPublished in: European radiology (2020)
• The sT1w/T2w ratio can detect MSA-C-related changes in the middle cerebellar peduncle, even in the early stages of the disorder. • The middle cerebellar peduncle sT1w/T2w ratio correlated with a cerebellar ataxia score in early MSA-C patients.