Mechanism of Vaginal Epithelial Cell Pyroptosis Induced by the NLRP3 Inflammasome in Vulvovaginal Candidiasis.
Yongmei PengYanan XuSainan LiMingkun ShaoZijia ShenWenjin QiPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2024)
C. albicans activated the NLRP3 inflammasome to induce vaginal epithelial cell pyroptosis. MCC950 inhibited the NLRP3 inflammasome, reduced vaginal epithelial cell pyroptosis, and decreased the release of inflammatory cytokines.
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