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Evaluation of the activity of cefepime/enmetazobactam against Enterobacterales bacteria collected in Europe from 2019 to 2021, including third-generation cephalosporin-resistant isolates.

Ian MorrisseyStephen HawserNimmi KothariNathalie DunkelJuan QuevedoAdam BelleyAnne Santerre HenriksenMarie Attwood
Published in: Journal of global antimicrobial resistance (2024)
Cefepime/enmetazobactam was highly active against Enterobacterales isolates, especially those resistant to third-generation cephalosporins. These data suggest that cefepime/enmetazobactam could be used as a carbapenem-sparing agent to replace piperacillin/tazobactam.
Keyphrases
  • gram negative
  • multidrug resistant
  • klebsiella pneumoniae
  • electronic health record
  • escherichia coli
  • drug resistant
  • data analysis
  • artificial intelligence