Evaluation of the activity of cefepime/enmetazobactam against Enterobacterales bacteria collected in Europe from 2019 to 2021, including third-generation cephalosporin-resistant isolates.
Ian MorrisseyStephen HawserNimmi KothariNathalie DunkelJuan QuevedoAdam BelleyAnne Santerre HenriksenMarie AttwoodPublished in: Journal of global antimicrobial resistance (2024)
Cefepime/enmetazobactam was highly active against Enterobacterales isolates, especially those resistant to third-generation cephalosporins. These data suggest that cefepime/enmetazobactam could be used as a carbapenem-sparing agent to replace piperacillin/tazobactam.