The Value of the Second QuantiFERON-TB Gold-Plus Antigen Tube at Diagnosis and at Treatment Completion in Spanish Children With Tuberculosis.

Aleix Soler-GarciaAnna GamellManuel MonsonísJosé Javier Korta-MuruaMaría EspiauElena Rincón-LópezPaula Rodríguez-MolinoTomàs Pérez-PorcunaMatilde Bustillo-AlonsoBegoña SantiagoMarc TebrueggeAntoni Noguera-Juliannull null

Published in: The Pediatric infectious disease journal (2023)

We studied 295 children (tuberculosis disease, n = 159; latent tuberculosis infection, n = 136) with positive QuantiFERON-TB Gold-Plus assay results. No significant differences between first and second antigen tube interferon-gamma responses were detected, irrespective of patient and disease characteristics at diagnosis. Of patients with a repeat assay after treatment completion (n = 65), only 16.9% converted to negative results.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
young adults
hiv aids
high throughput
dendritic cells
emergency department
adverse drug
silver nanoparticles
combination therapy
human immunodeficiency virus