Tracking Radiolabeled Endothelial Microvesicles Predicts Their Therapeutic Efficacy: A Proof-of-Concept Study in Peripheral Ischemia Mouse Model Using SPECT/CT Imaging.
Romain GiraudAnaïs MoyonStéphanie SimonciniAnne-Claire DuchezVincent NailCorinne ChareyreAhlem BouhlelLaure BalasseSamantha FernandezLoris VallierGuillaume HacheFlorence SabatierFrançoise Dignat-GeorgeRomaric LacroixBenjamin GuilletPhilippe GarriguePublished in: Pharmaceutics (2022)
This concept is a major asset for investigating the biodistribution of LEVs issued from other cell types, including cancer, thus partly contributing to better knowledge and understanding of their fate after injection.
Keyphrases
- mouse model
- papillary thyroid
- high resolution
- single cell
- healthcare
- computed tomography
- cell therapy
- squamous cell
- image quality
- contrast enhanced
- dual energy
- pet ct
- magnetic resonance imaging
- pet imaging
- stem cells
- squamous cell carcinoma
- lymph node metastasis
- childhood cancer
- magnetic resonance
- mass spectrometry
- young adults
- bone marrow
- chemotherapy induced