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Radiomics risk score may be a potential imaging biomarker for predicting survival in isocitrate dehydrogenase wild-type lower-grade gliomas.

Chae Jung ParkKyunghwa HanHwiyoung KimSung Soo AhnYoon Seong ChoiYae Won ParkJong Hee ChangSe Hoon KimRajan JainSeung-Koo Lee
Published in: European radiology (2020)
• Isocitrate dehydrogenase wild-type lower-grade gliomas with histologic grades II and III follow heterogeneous clinical outcomes, which necessitates further risk stratification. • Radiomics risk scores derived from MRI independently predict survival even after incorporating strong clinical prognostic features (hazard ratios 6.148-9.479). • Radiomics risk scores derived from MRI have the potential to improve survival prediction when added to clinical features (integrated areas under the receiver operating characteristic curves increased from 0.726 to 0.780-0.797).
Keyphrases
  • wild type
  • contrast enhanced
  • magnetic resonance imaging
  • lymph node metastasis
  • high grade
  • free survival
  • high resolution
  • squamous cell carcinoma
  • risk assessment
  • photodynamic therapy
  • fluorescence imaging