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Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection.

Valerine C ChundaManuel RitterAyukenchengamba BateNarcisse V T GandjuiMathias E EsumFanny F FombadAbdel J NjouendouPatrick W C NdongmoMark J TaylorAchim HoeraufLaura E LaylandJoseph D TurnerSamuel Wanji
Published in: Parasites & vectors (2020)
This study shows that although host immunity remains comparable to naive mice, clearance of L. loa life-cycle development stages can induce immune cell memory leading to cytokine, chemokine and immunoglobulins secretion patterns which might contribute to immunity and protection against reinfection.
Keyphrases
  • life cycle
  • immune response
  • high fat diet induced
  • hiv infected
  • dendritic cells
  • toll like receptor
  • wild type
  • insulin resistance