A novel 1,8-naphthalimide-based fluorescent chemosensor for the detection of HSA in living cells.
Liuting MoWanqi HeYonghe TangDanlian LiangChan YangWeiying LinPublished in: Luminescence : the journal of biological and chemical luminescence (2022)
Human serum albumin (HSA) is an essential protein for maintaining human health. Accurate detection and quantification of HSA are of great significance for disease diagnosis and biochemical research. Here, a new HSA fluorescent probe BNPE based on the 1,8-naphthalimide fluorophore was designed and synthesized. The probe could recognize HSA through a twisted intramolecular charge transfer mechanism, effectively avoid the interference of most substances, and realize HSA fluorescence imaging in living cells.