A rapid approach towards a specific carbazolelactam system related to calothrixin B.
Zizhen WangSheng LiuPublished in: Organic & biomolecular chemistry (2024)
Reported here is a rapid and versatile synthetic approach towards the specific pentacyclic carbazolelactams related to calothrixin B. The crucial transformation is an acid-promoted cascade involving a dehydration/electrocyclization/C-N bond cleavage/lactamization sequence.