Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Min YuLiyao PengPing LiuMingxia YangHong ZhouYirui DingJingjing WangWen HuangQi TanYanli WangWeiping XieHui KongHong WangPublished in: Drug design, development and therapy (2020)
Taken together, our findings suggest that PF ameliorates BMPR2 down-regulation-mediated EndMT and thereafter alleviates SuHx-induced PAH in rats.