Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis.

Jan-Christopher KampLavinia NeubertHelge Stark Jan B HinrichsCaja BoekhoffAllison D SeidelFabio IusAxel Haverich Jens GottliebTobias WeltePeter BraubachFlorian LaengerMarius M HoeperMark P KuehnelDanny D Jonigk

Published in: Cells (2022)

These results demonstrate that FF of end-stage IPF and sarcoidosis lungs, although different in initiation, are similar in gene and protein expression, encouraging further studies on the use of antifibrotic agents in sarcoidosis.

Keyphrases

idiopathic pulmonary fibrosis
gene expression
interstitial lung disease
dna methylation
pulmonary hypertension
genome wide
copy number
case control
transcription factor
pulmonary fibrosis