In from the cold: M-protein light chain glycosylation is positively associated with cold agglutinin titer levels.
Justin E JuskewitchJosiah D MurrayAndrew P NorganSheila K MoldenhauerCraig D TauscherEapen K JacobDavid L MurrayPublished in: Transfusion (2021)
M-protein LC glycosylation is significantly associated with higher CA titer levels. Given the role that antibody glycosylation can play in antibody half-life and complement fixation, further studies are needed to clarify the effects of LC glycosylation within the context of CAD.