Dexmedetomidine attenuates oxidative stress induced lung alveolar epithelial cell apoptosis in vitro.

Jian CuiHailin ZhaoChunyan WangJames J SunKaizhi LuDaqing Ma

Published in: Oxidative medicine and cellular longevity (2015)

Our study demonstrated that Dex protected lung alveolar epithelial cells from apoptotic injury, cell cycle arrest, and loss of cell adhesion induced by H2O2 through enhancing the cell survival and proliferation.

Keyphrases

cell cycle arrest
cell death
cell adhesion
pi k akt
signaling pathway
oxidative stress
endoplasmic reticulum stress
acute kidney injury
anti inflammatory