Metastasis in patients with hepatocellular carcinoma: Prevalence, determinants, prognostic impact and ability to improve the Barcelona Clinic Liver Cancer system.
Chia-Yang HsuPo-Hong LiuShu-Yein HoYi-Hsiang HuangYun-Hsuan LeeRheun-Chuan LeeTeddy S NagariaMing-Chih HouTeh-Ia HuoPublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
Metastasis is not uncommon, and is strongly associated with tumoural factors and poor long-term survival in hepatocellular carcinoma. Modification of the Barcelona Clinic Liver Cancer system based on vascular invasion and metastasis may further improve its predictive accuracy in advanced stage patients.