Hydrogen bonding enhanced drug-polymer interaction for efficient drug loading and delivery.
Xiaotian QuJunran LiYishu YuJie YangPublished in: Soft matter (2024)
A carrier design strategy of hydrogen bonding enhanced drug-carrier interaction is developed to prepare a polymeric nanomedicine with high drug loading content and superb loading efficiency. Moreover, a morphology transition from spherical to cylindrical micelles is observed upon increasing drug loading content, which can open up a new way for controlling the morphology of the polymeric nanomedicine.