Maternal transfer of IgA and IgG SARS-CoV-2 specific antibodies transplacentally and via breast milk feeding.

Mohammad M SajadiNarjes ShokatpourMadeleine PurcellZahra Rikhtegaran TehraniAllison LankfordAllison BathulaJames D CampbellElizabeth Adrianne HammershaimbKristopher B DeatrickCasey BorDawn M ParsellColleen DuganAndrea R LevineSabrina C RamelliDaniel S ChertowDaniel L HerrKapil K SahariaGeorge K LewisAlison Grazioli

Published in: PloS one (2023)

Vaccination antepartum followed by breast milk feeding appears to be the best way to provide systemic and local anti-SARS-CoV-2 antibodies for infants. The presence of high titer SARS-CoV-2-specific IgA in the nose of infants points to the potential importance of breast milk feeding early in life for maternal transfer of mucosal IgA antibodies. Expectant mothers should consider becoming vaccinated antepartum and consider breast milk feeding for optimal transfer of systemic and mucosal antibodies to their infants.

Keyphrases

sars cov
respiratory syndrome coronavirus
birth weight
ulcerative colitis
pregnant women
climate change
pregnancy outcomes
risk assessment
drug induced
gestational age
preterm birth