[P 3 ]PP, a stable, long-acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta-cell-protective effects in obesity-associated diabetes.

Neil TandayWuyun ZhuAndrei I TarasovPeter R FlattNigel Irwin

Published in: Diabetes, obesity & metabolism (2024)

Collectively, these data highlight for the first time the potential of enzymatically stable PP analogues for the treatment of obesity and related diabetes.

Keyphrases

type diabetes
weight loss
glycemic control
weight gain
insulin resistance
metabolic syndrome
cardiovascular disease
high fat diet induced
single cell
cell therapy
physical activity
machine learning
human health
risk assessment
mesenchymal stem cells
artificial intelligence