Molecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization.

Toney Thomas PoovelikunnelPaulo E BudriAnna C Shore David C ColemanHilary HumphreysDeirdre Fitzgerald-Hughes

Published in: Antimicrobial agents and chemotherapy (2018)

Sequential methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients following attempted mupirocin nasal decolonization showed an increase in mupirocin resistance (MR) from 6.6% to 20%. MR isolates from patients who failed decolonization yielded indistinguishable spa types and carried multiple antimicrobial and antiseptic resistance genes, which may guide infection control and prevention.

Keyphrases

methicillin resistant staphylococcus aureus
staphylococcus aureus
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
magnetic resonance
contrast enhanced
risk factors
prognostic factors
magnetic resonance imaging
gene expression
bioinformatics analysis