ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men.

Kageumi TakenoYoshifumi TamuraSaori KakehiHideyoshi KagaRyuzo KawamoriHirotaka Watada

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our data suggest that high-alcohol intake-dependent and independent hepatic insulin resistance and reduced fasting glucose clearance due to high alcohol intake could be a relatively upstream metabolic abnormality in ALDH2 rs671 G/G carriers.

Keyphrases

insulin resistance
blood glucose
type diabetes
metabolic syndrome
weight gain
alcohol consumption
high fat diet
skeletal muscle
electronic health record
blood pressure
polycystic ovary syndrome
physical activity
data analysis
deep learning