Brain serotonin 4 receptor binding is inversely associated with verbal memory recall.

Dea Siggaard StenbaekPatrick M FisherBrice OzenneEmil AndersenLiv V HjordtBrenda McMahonSteen G HasselbalchVibe G FrokjaerGitte M Knudsen

Published in: Brain and behavior (2017)

Our findings replicate our previous observation of a negative association between 5-HT 4R binding and memory performance in an independent cohort and provide novel evidence linking 5-HT 4R binding, as a biomarker for synaptic 5-HT levels, to the mnestic processing of positive and neutral word stimuli in healthy humans.

Keyphrases

working memory
binding protein
dna binding
white matter
resting state
functional connectivity
transcription factor
prefrontal cortex