Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK).

Rolf GremplerMichael WolffEric SimonRamona SchmidClaudia EiseleKathrin RieberElke FischerSonja MettelOgsen GabrielyanDenis DelicGerd LuippoldNorbert Redeman

Published in: PloS one (2018)

GPNMB has been identified as a translatable target engagement biomarker for use in clinical studies.

Keyphrases

protein kinase
social media
small molecule
high throughput
skeletal muscle