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Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma.

Julie A TomolonisXin XuKshiti H DholakiaChunchao ZhangLinjie GuoAmy N CourtneySiyue WangJulien BalzeauGabriel A BarragánGengwen TianErica J Di PierroLeonid S Metelitsa
Published in: Journal for immunotherapy of cancer (2023)
We have described a novel mechanism of tumor-promoting inflammation in NB that is strongly associated with patient outcome and could be targeted with therapy.
Keyphrases
  • oxidative stress
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  • single cell
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  • case report
  • cancer therapy
  • peripheral blood
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  • drug delivery
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