Precision therapy of 6-mercaptopurine in Chinese children with acute lymphoblastic leukaemia.

Yue ZhouLi WangXiao-Ying ZhaiLi WenFang TangFan YangXi-Ting LiuLei DongLi-Juan ZhiHai-Yan ShiGuo-Xiang HaoYi ZhengEvelyne Jacqz-AigrainTian-You WangWei Zhao

Published in: British journal of clinical pharmacology (2020)

Our findings support the idea that predetermination of genotypes and monitoring of thiopurine metabolism for Chinese paediatric patients afflicted by ALL is necessary to effectively predict the efficacy of treatments and to minimize the adverse effects of 6-MP maintenance therapy.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
intensive care unit
peritoneal dialysis
prognostic factors
patient reported outcomes
patient reported
drug induced