Can the genetic polymorphisms of the folate metabolism have an influence in the polycystic ovary syndrome?
Tayssia Beatriz Dos SantosHelena Korres de PaulaMarly Aparecida Spadotto BalarinRoseane Lopes Silva-GreccoMarco Fábio Prata LimaElisabete Aparecida Mantovanni Rodrigues de ResendeMariana Kefalás de Oliveira GomesMariangela Torreglosa Ruiz CintraPublished in: Archives of endocrinology and metabolism (2019)
In our casuistry, the polymorphic homozygous of MTRR A66G polymorphism gene and heterozygous of RFC-1 A80G polymorphism gene, the haplotype T-C C677T and A1298C polymorphisms of MTHFR gene, can be associated with protective factors for the disease.