Exploring Cell Migration Mechanisms in Cancer: From Wound Healing Assays to Cellular Automata Models.
Giorgia MigliaccioRosalia FerraroZhihui WangVittorio CristiniPrashant DograSergio CasertaPublished in: Cancers (2023)
Our analyses led to the formulation of a power law equation derived from just a few input parameters that accurately describes the governing mechanism of wound healing. This groundbreaking research provides a powerful tool for the pharmaceutical industry. In fact, this approach proves invaluable for the discovery of novel compounds aimed at disrupting cell migration, assessing the efficacy of prospective drugs designed to impede cancer invasion, and evaluating the immune system's responses.