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Design, Synthesis and Evaluation of Benzimidazole Hybrids to Inhibit Acetylcholinesterase and COX for Treatment of Alzheimer's Disease.

Sukhvir KaurRicha MinhasShivam MishraBirpal KaurYogita BansalGulshan Bansal
Published in: Central nervous system agents in medicinal chemistry (2022)
The findings indicate that Benzimidazole hybrids utilizing ibuprofen and pyrrolidine moiety may prove a useful template for the development of new chemical moieties against AD with multiple potencies.
Keyphrases
  • molecular docking
  • mass spectrometry