Clamping Cortisol and Testosterone Mitigates the Development of Insulin Resistance during Sleep Restriction in Men.
Peter Y LiuDarian Lawrence-SidebottomKatarzyna PiotrowskaWenyi ZhangAli IranmaneshRichard J AuchusJohannes D VeldhuisHans P A Van DongenPublished in: The Journal of clinical endocrinology and metabolism (2021)
Fixing cortisol-testosterone exposure mitigates the development of insulin resistance and hyperinsulinemia, but not hyperglycemia, from sustained sleep restriction in men. The interplay between cortisol and testosterone may be important as a mechanism by which sleep restriction impairs metabolic health.
Keyphrases
- insulin resistance
- replacement therapy
- sleep quality
- physical activity
- adipose tissue
- metabolic syndrome
- type diabetes
- high fat diet
- polycystic ovary syndrome
- healthcare
- public health
- middle aged
- skeletal muscle
- mental health
- high fat diet induced
- radiation induced
- smoking cessation
- oxidative stress
- risk assessment
- social media
- diabetic rats
- health promotion
- glycemic control
- climate change