Molecular alterations of human lumbar yellow ligament related to the process of intervertebral disk degeneration and stenosis.
Delio Eulalio MartinsMarcelo WajchenbergJuliana Mora VeridianoThérèse Rachell TheodoroOlga Maria de Toledo CorreaMaria Aparecida da Silva PinhalPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2019)
Two layers compose the elastic system of the normal ligamentum flavum, where the deep portion is mainly responsible for its elasticity (elaunin fibers), while its resistance depends on the concentration of oxytalan fibers, which are more present in the superficial layer. Ligamentum flavum in the stenosis samples presents more mononuclear infiltrate and more degraded elastic fibers with a higher number of vessels in its deep portion. These slides can be retrieved under Electronic Supplementary Material.