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Hormones, age, and sex affect platelet responsiveness in vitro.

Jamie B HadleyMarguerite R KelherJulia R ColemanKathleen K KellyLarry J DumontOrlando EsparzaAnirban BanerjeeMitchell J CohenKenneth JonesChristopher C Silliman
Published in: Transfusion (2022)
Platelets have sex- and age-specific aggregation, receptor expression, and metabolism. Testosterone decreases platelet function dependent on the stimulus, age, and sex. Similarly, platelet metabolism has varying responses to sex hormones with baseline metabolic differences dependent upon sex and age.
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