Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates.

Jinar RostamiTobias MothesMahshad KolahdouzanOlle ErikssonMohsen MoslemJoakim BergströmMartin IngelssonPaul O'CallaghanLuke M HealyAnna FalkAnna Erlandsson

Published in: Journal of neuroinflammation (2021)

Taken together, our data demonstrate the importance of astrocyte and microglia interactions in Aβ/αSYN clearance, highlighting the relevance of glial cellular crosstalk in the progression of AD- and PD-related brain pathology.

Keyphrases

neuropathic pain
inflammatory response
spinal cord
resting state
electronic health record
spinal cord injury
white matter
big data
functional connectivity
data analysis
brain injury
multiple sclerosis
machine learning