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The Dual Endothelin-1 Antagonist Aprocitentan Alleviates Mitochondrial Oxidative Stress in Human Cardiac Fibroblasts.

Fahimeh VarzidehStanislovas S JankauskasUrja JainLauren SoderquistEsther Densu AgyapongUrna KansakarJoseph H Taube
Published in: European heart journal. Cardiovascular pharmacotherapy (2024)
Keyphrases
  • oxidative stress
  • endothelial cells
  • induced pluripotent stem cells
  • dna damage
  • left ventricular
  • induced apoptosis
  • diabetic rats
  • extracellular matrix
  • heart failure
  • mouse model
  • endoplasmic reticulum stress