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Consistent Correlation between MTHFR and Vascular Thrombosis in Neonates-Case Series and Clinical Considerations.

Catalin Gabriel CirstoveanuNicoleta CalinCarmen HeriseanuCristina FilipCorina Maria VasileIrina MargarintVeronica MarcuMihai Cornel Traian DimitriuLiliana PlesSorin TarnoveanuMihaela Bizubac
Published in: Journal of clinical medicine (2023)
The particularity of this case series is that every patient in our unit who developed thrombi had a positive genetic result for MTHFR mutations. MTHFR mutations should be regarded as a thrombotic risk factor for critically ill patients, and screening for MTHFR mutations should be performed in every admitted patient to intensive care units, thus achieving the prevention of thrombi.
Keyphrases
  • intensive care unit
  • case report
  • pulmonary embolism
  • copy number
  • preterm birth
  • acute respiratory distress syndrome
  • extracorporeal membrane oxygenation