Congenital anomalies of the kidney and urinary tract: antenatal diagnosis, management and counselling of families.
Emma Y X WalkerPaul WinyardMatko MarlaisPublished in: Pediatric nephrology (Berlin, Germany) (2023)
Congenital anomalies of the kidney and urinary tract are collectively one of the most commonly diagnosed antenatal conditions. Clinicians have several tools available to diagnose anomalies, including imaging, biomarkers, family history and genetic studies. In certain cases, antenatal interventions such as vesico-amniotic shunting may be considered to improve postnatal outcomes.Congenital kidney anomalies detected antenatally can vary in clinical significance from almost no impact postnatally to significant morbidity and perinatal mortality. Prognosis broadly depends on kidney size, structure and amount of amniotic fluid, alongside genetics and family history, and progression on subsequent scans. It is important to counsel parents appropriately using a parent-focused and personalised approach. The use of a multidisciplinary team should always be considered.
Keyphrases
- urinary tract
- pregnant women
- preterm birth
- palliative care
- high resolution
- computed tomography
- quality improvement
- gene expression
- cardiovascular disease
- adipose tissue
- magnetic resonance imaging
- mass spectrometry
- dna methylation
- magnetic resonance
- bone marrow
- risk factors
- insulin resistance
- metabolic syndrome
- men who have sex with men
- antiretroviral therapy
- weight loss
- hiv testing