Novel coronavirus (SARS-CoV-2) infection in a renal transplant recipient: Case report.
Ling NingLei LiuWenyuan LiHongtao LiuJizhou WangZiqin YaoShengyu ZhangDesheng ZhaoBjörn NashanAizong ShenLianxin LiuLei LiPublished in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2020)
An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure, and no pharmacological therapies of proven efficacy yet exist. We report a case of SARS-CoV-2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of cyclosporine in patients treated with lopinavir/ritonavir; the routine treatment of corticosteroid can be continued. This is a rare report of SARS-CoV-2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity, and outcome of SARS-CoV-2 infections in solid organ transplant recipients.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- acute respiratory distress syndrome
- coronavirus disease
- case report
- extracorporeal membrane oxygenation
- end stage renal disease
- respiratory failure
- mechanical ventilation
- newly diagnosed
- chronic kidney disease
- ejection fraction
- liver failure
- peritoneal dialysis
- combination therapy
- replacement therapy
- aortic dissection
- artificial intelligence
- data analysis
- patient reported
- respiratory tract