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Is sleep apnea underdiagnosed in adult patients with osteogenesis imperfecta? -a single-center cross-sectional study.

Heidi ArponenAdel BachourLeif BäckHelena ValtaAntti MäkitieJanna Waltimo-SirénOuti Mäkitie
Published in: Orphanet journal of rare diseases (2018)
Seeing that the usual predictors showed no association with occurrence of sleep apnea, we conclude that obstructive sleep apnea may easily be left as an undetected disorder in individuals with OI. Recurrent nocturnal hypoxia due to episodes of apneas can even affect bone metabolism, thereby further aggravating bone fragility in patients with OI.
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