Use of α1-adrenoceptor antagonists tamsulosin and alfuzosin and the risk of Alzheimer's disease.
Laura LatvalaMiia TiihonenTeemu J MurtolaSirpa HartikainenAnna-Maija TolppanenPublished in: Pharmacoepidemiology and drug safety (2022)
Our findings, especially the lack of dose-response-relationship and attenuation after mediator adjustment, do not provide strong support for the previous hypothesis on α1-adrenoceptor antagonists as a risk factor for dementia.