Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population.

Miaomiao ZhouYuwan LinLin LuZhiling ZhangWenyuan GuoGuoyou PengWenlong ZhangZiting ZhuZhuohua WuMingshu MoXinling YangXiaoqin ZhuChaojun ChenXiang ChenPingyi Xu

Published in: The journal of gene medicine (2021)

Our data suggested that C allele of rs514049 in ADAM10 may increase the risk of PD in Chinese Han population, especially in males. The decreased plasma levels are probably involved in PD development.

Keyphrases

copy number
late onset
electronic health record
genome wide
big data
amyotrophic lateral sclerosis
transcription factor